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Nevada Pain Care Treatments

HYALGAN® Injection for Knee Pain

During this non-operative, outpatient procedure, the physician injects a pain relief medication called HYALGAN® into the knee joint. The HYALGAN® will help the knee move smoothly, reducing or relieving the pain of osteoarthritis.

Treatment Quick Facts

What is this treatment for?

HYALGAN® is designed to treat pain due osteoarthritis of the knee in patients who have not responded to conservative therapies and to simple pain medications (ie. acetaminophen). 

How is this treatment administered?

Your provider will inject the HYALGAN into your knee joint. It bonds with the knee's synovial fluid (the thick lubricating fluid inside your joint). The HYALGAN will cushion your knee and help it move smoothly.

How long is this treatment?

The procedure typically takes about 15-30 minutes and may be repeated if necessary.
Watch and learn

Please take a moment to watch a quick procedure video.

If you have any questions, please contact us and we would be happy to help you.

About HYALGAN® Injection for Knee Pain


The main component of HYALGAN® is a naturally-derived material called hyaluronan. This substance reduces your pain by cushioning and lubricating your knee joint. Hyaluronan is naturally found in the body and is typically found in particularly large amounts in joint tissue and in the fluid within the joint, or the synovial fluid. HYALGAN® is injected directly into the knee.

Is it right for me?

If you are experiencing knee pain caused from osteoarthritis that has not responded to conservative therapies, you may be a good candidate for a HYALGAN® injection.

What is the procedure like?

To begin, your knee is numbed with a local anesthetic. A needle is carefully inserted into your knee joint. The doctor uses a fluoroscope (that's a video X-ray device that shows moving images) to watch the needle inside your knee. To make sure the needle is in the right place, the doctor injects some dye. It shows up clearly on the fluoroscope. The doctor makes sure the dye enters the space around the joint. Without moving the needle, the doctor removes the dye syringe. It's replaced with a syringe of HYALGAN. The doctor injects it into your joint. It bonds with the knee's synovial fluid (that's the thick lubricating fluid inside your joint). The HYALGAN will cushion your knee and help it move smoothly.

What happens after the procedure?

After the injection, your knee is bandaged. A series of three to five HYALGAN injections will complete your regimen. You'll get one each week. Pain relief usually begins after the third injection, and it can last for up to six months. You may benefit from physical therapy, too. For more information, speak to a Nevada Pain Care provider.

Is this treatment right for you?

Schedule an appointment to discuss this treatment with your provider.

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